Synthesis, characterization and antimicrobial activity of some novel benzimidazole derivatives
نویسندگان
چکیده
منابع مشابه
Synthesis Antimicrobial Activity and Chemotherapeutic Potential some Novel Benzimidazole Derivatives
Benzimidazole derivates play vital role in biological field such as antimicrobial, antiviral, antidiabetic, and anticancer activity. Therapeutic significance of these clinically useful drugs in treatment of microbial infections encouraged the development of some more potent and significant compounds. With the purpose of finding new chemical entities with enhanced antimicrobial activity, a serie...
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The purpose of the present study was to synthesize some novel terpenoids substituted N-(1Hbenzimidazol-2-yl) hydrazine-carboxamide derivatives for possible antimicrobial activity. The synthesized compounds were tested against a panel of Gram-negative (Gm-ve), Gram-positive (Gm+ve) bacterial and fungal strains. The results of MIC tests against both type of bacteria revealed that compounds 5a and...
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A new series of 2,5- and/or 6-substituted benzoxazoles (7a-f), benzimidazoles (8a-g) holding cyclohexyl or cyclopentyl moieties at position 2 and 5- or 6-substituted-2-cyclohexylaminomethylbenzoxazoles (9a, b) was synthesized in order to determine their antimicrobial activities and feasible structure-activity relationships. The synthesized compounds were tested in vitro against three Gram-posit...
متن کاملSynthesis and antimicrobial activities of some new benzimidazole derivatives.
Some benzimidazolylbenzamides were synthesized and their antimicrobial activities against Staphylococcus aureus, Streptococcus faecalis, Bacillus subtilis, Escherichia coli, Pseudomonas aeruginosa and Candida albicans evaluated. It was shown that the compound 14 exhibited the best activity against B. subtilis, P. aeruginosa and C. albicans.
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ژورنال
عنوان ژورنال: Journal of Advanced Pharmaceutical Technology & Research
سال: 2014
ISSN: 2231-4040
DOI: 10.4103/2231-4040.126983